Invention Grant
US08173426B2 Muller cells de-differentiated to cells expressing markers of neural cell progenitors
有权
Muller细胞被分化成表达神经细胞祖细胞标志物的细胞
- Patent Title: Muller cells de-differentiated to cells expressing markers of neural cell progenitors
- Patent Title (中): Muller细胞被分化成表达神经细胞祖细胞标志物的细胞
-
Application No.: US10580770Application Date: 2004-12-03
-
Publication No.: US08173426B2Publication Date: 2012-05-08
- Inventor: Gloria Astrid Limb , Peng Tee Khaw
- Applicant: Gloria Astrid Limb , Peng Tee Khaw
- Applicant Address: GB London
- Assignee: The Institute of Ophthalmology
- Current Assignee: The Institute of Ophthalmology
- Current Assignee Address: GB London
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Priority: GB0328021.1 20031203
- International Application: PCT/GB2004/005101 WO 20041203
- International Announcement: WO2005/054447 WO 20050616
- Main IPC: C12N5/00
- IPC: C12N5/00
Abstract:
A method for the production of retinal cells, useful in transplantation therapy, comprises: (i) obtaining one or more mammalian adult Müller cells; and (ii) culturing the cells in the presence of an extracellular matrix protein and a growth factor to thereby induce dedifferentiation of the Müller cells into a progenitor phenotype.
Public/Granted literature
- US20070248644A1 Muller Stem Cells Public/Granted day:2007-10-25
Information query
