Invention Grant
US08173612B2 Chemotherapy involving antisense oligonucleotides for preventing and/or treating pulmonary fibrosis
有权
涉及用于预防和/或治疗肺纤维化的反义寡核苷酸的化疗
- Patent Title: Chemotherapy involving antisense oligonucleotides for preventing and/or treating pulmonary fibrosis
- Patent Title (中): 涉及用于预防和/或治疗肺纤维化的反义寡核苷酸的化疗
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Application No.: US11521843Application Date: 2006-09-15
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Publication No.: US08173612B2Publication Date: 2012-05-08
- Inventor: Rahul K. Nath , Usha Nath
- Applicant: Rahul K. Nath , Usha Nath
- Agency: The Matthews Firm
- Priority: GB9929487.8 19991215; WOPCT/GB00/04741 20001212
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12Q1/68
Abstract:
The invention provides, in the treatment of malignant tumors, antisense DNA oligonucleotides which are effective in inhibiting the expression of a wild type COL1A1 gene, in combination with a chemotherapy drug, typically bleomycin, cyclophosphamide, or methotrexate, which otherwise is known to cause lung disease such as pulmonary fibrosis.
Public/Granted literature
- US20110172162A1 Chemotherapy involving antisense oligonucleotides for preventing and/or treating pulmonary fibrosis Public/Granted day:2011-07-14
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