Invention Grant
- Patent Title: Modulation of mesenchymal and metastatic cell growth
- Patent Title (中): 间质和转移细胞生长的调节
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Application No.: US11525715Application Date: 2006-09-22
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Publication No.: US08173613B2Publication Date: 2012-05-08
- Inventor: Douglas B. Spicer
- Applicant: Douglas B. Spicer
- Applicant Address: US ME Scarborough
- Assignee: Maine Medical Center
- Current Assignee: Maine Medical Center
- Current Assignee Address: US ME Scarborough
- Agency: Pierce Atwood LLP
- Agent Kevin M. Farrell, Esq.; David J. Wilson, Esq.
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/00 ; C12N5/02 ; A61K48/00 ; A61K39/00 ; C07H21/04
Abstract:
The present invention relates to compositions and methods for the modulation of metastatic and mesenchymal cell growth and mobility via the regulation of the formation of Twist/Twist homodimers and Twist/E heterodimers. The present invention also relates to methods for screening agents and compound libraries for molecules that function to modulate the formation of Twist/Twist homodimers, Twist/E protein heterodimers or their upstream or downstream effector molecules.
Public/Granted literature
- US20070093442A1 Modulation of mesenchymal and metastatic cell growth Public/Granted day:2007-04-26
Information query
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