Invention Grant
US08173634B2 Polymorphic form of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic
有权
1-（4- {1 - [（E）-4-环己基-3-三氟甲基 - 苄氧亚氨基] - 乙基} -2-乙基 - 苄基） - 氮杂环丁烷-3-羧酸的多晶型
![Polymorphic form of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic](/docs/US/2012-05-08/US08173634B2/abs.jpg.600x600.jpg)
- Patent Title: Polymorphic form of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic
- Patent Title (中): 1-（4- {1 - [（E）-4-环己基-3-三氟甲基 - 苄氧亚氨基] - 乙基} -2-乙基 - 苄基） - 氮杂环丁烷-3-羧酸的多晶型
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Application No.: US13140453Application Date: 2009-12-17
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Publication No.: US08173634B2Publication Date: 2012-05-08
- Inventor: Yugang Liu , Dimitris Papoutsakis , Elizabeth Roddy
- Applicant: Yugang Liu , Dimitris Papoutsakis , Elizabeth Roddy
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Karen DeBenedictis
- International Application: PCT/US2009/068346 WO 20091217
- International Announcement: WO2010/071794 WO 20100624
- Main IPC: A61K31/397
- IPC: A61K31/397 ; C07D205/04
![Polymorphic form of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic](/abs-image/US/2012/05/08/US08173634B2/abs.jpg.150x150.jpg)
Abstract:
This invention relates to a novel crystalline form (Form A) of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic acid (Compound I), to pharmaceutical compositions comprising this crystalline form, to processes for forming it and to its use in medical treatment.
Public/Granted literature
- US20110251170A1 NEW POLYMORPHIC FORM OF 1-(4--2-ETHYL-BENZYL)-AZETIDINE-3-CARBOXYLIC Public/Granted day:2011-10-13
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