Invention Grant
- Patent Title: Isoxazole-isoxazoles and isoxazole-isothiazoles
- Patent Title (中): 异恶唑异恶唑和异恶唑异噻唑
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Application No.: US12704548Application Date: 2010-02-12
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Publication No.: US08173652B2Publication Date: 2012-05-08
- Inventor: Maria-Clemencia Hernandez , Roland Jakob-Roetne , Matthew C. Lucas , Andrew Thomas
- Applicant: Maria-Clemencia Hernandez , Roland Jakob-Roetne , Matthew C. Lucas , Andrew Thomas
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- Priority: EP09153162 20090219
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/42 ; A61K31/454 ; C07D413/06 ; C07D413/14
Abstract:
The present invention is concerned with isoxazole-isoxazoles and isoxazole-isothiazoles of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as cognitive enhancers or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.
Public/Granted literature
- US20100210651A1 ISOXAZOLE-ISOXAZOLES AND ISOXAZOLE-ISOTHIAZOLES Public/Granted day:2010-08-19
Information query
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