Invention Grant
- Patent Title: Bicyclic anilide heterocyclic CGRP receptor antagonists
- Patent Title (中): 双环酰苯胺杂环CGRP受体拮抗剂
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Application No.: US12595874Application Date: 2008-04-11
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Publication No.: US08173655B2Publication Date: 2012-05-08
- Inventor: Ian M. Bell , Harold G. Selnick , Craig A. Stump
- Applicant: Ian M. Bell , Harold G. Selnick , Craig A. Stump
- Applicant Address: US NJ Rahway
- Assignee: Merck, Sharp & Dohme Corp.
- Current Assignee: Merck, Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Nicole M. Beeler; Gerard M. Devlin
- International Application: PCT/US2008/004694 WO 20080411
- International Announcement: WO2008/130512 WO 20081030
- Main IPC: A61K31/438
- IPC: A61K31/438 ; A61K31/498
Abstract:
Compounds of formula I: (wherein variables A1, A2, B, m, n, J, R4, G1, G2, G3 and Y are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Public/Granted literature
- US20100093759A1 BICYCLIC ANILIDE HETEROCYCLIC CGRP RECEPTOR ANTAGONISTS Public/Granted day:2010-04-15
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