Invention Grant
US08173670B2 Methods of using substituted isoxazolo pyridinones as dissociated glucocorticoids
有权
取代的异恶唑吡喃酮作为解离糖皮质激素的方法
- Patent Title: Methods of using substituted isoxazolo pyridinones as dissociated glucocorticoids
- Patent Title (中): 取代的异恶唑吡喃酮作为解离糖皮质激素的方法
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Application No.: US12686805Application Date: 2010-01-13
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Publication No.: US08173670B2Publication Date: 2012-05-08
- Inventor: Huaqiang Eric Xu , Yong Xu , Yuanzheng He
- Applicant: Huaqiang Eric Xu , Yong Xu , Yuanzheng He
- Applicant Address: US MI Grand Rapids
- Assignee: Van Andel Research Institute
- Current Assignee: Van Andel Research Institute
- Current Assignee Address: US MI Grand Rapids
- Agency: Honigman Miller Schwartz and Cohn LLP
- Agent Douglas H. Siegel
- Main IPC: A01N43/42
- IPC: A01N43/42

Abstract:
A method for treating a subject having an inflammatory or auto-immune disease with a substituted isoxazolo pyridinone. Also, a method for administering a substituted isoxazolo pyridinone to a cell to retain or increase glucocorticoid receptor transrepression activity with only minimal glucocorticoid receptor transactivation activity.
Public/Granted literature
- US20110251211A9 METHODS OF USING SUBSTITUTED ISOXAZOLO PYRIDINONES AS DISSOCIATED GLUCOCORTICOIDS Public/Granted day:2011-10-13
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