Invention Grant
- Patent Title: Quinolizidinone M1 receptor positive allosteric modulators
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Application No.: US12933799Application Date: 2009-03-11
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Publication No.: US08173672B2Publication Date: 2012-05-08
- Inventor: Scott D. Kuduk , Ronald K. Chang , Christina Ng Di Marco
- Applicant: Scott D. Kuduk , Ronald K. Chang , Christina Ng Di Marco
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Sylvia A. Ayler; Gerard M. Devlin
- International Application: PCT/US2009/036717 WO 20090311
- International Announcement: WO2009/117283 WO 20090924
- Main IPC: A61K31/44
- IPC: A61K31/44
Abstract:
The present invention is directed to compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.
Public/Granted literature
- US20110046145A1 Quinolizidinone M1 Receptor Positive Allosteric Modulators Public/Granted day:2011-02-24
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