Invention Grant
- Patent Title: Taste receptors of the T1R family from domestic cat
- Patent Title (中): 来自家猫的T1R家族的口感受体
-
Application No.: US12406334Application Date: 2009-03-18
-
Publication No.: US08173769B2Publication Date: 2012-05-08
- Inventor: Xia Li , Weihua Li , Danielle R. Reed , Alexander A. Bachmanov , Joseph G. Brand
- Applicant: Xia Li , Weihua Li , Danielle R. Reed , Alexander A. Bachmanov , Joseph G. Brand
- Applicant Address: US PA Philadelphia
- Assignee: Monell Chemical Senses Center
- Current Assignee: Monell Chemical Senses Center
- Current Assignee Address: US PA Philadelphia
- Agency: Woodcock Washburn LLP
- Main IPC: C07K14/705
- IPC: C07K14/705 ; C07K19/00

Abstract:
The present invention relates to the discovery of several genes of the domestic cat (Felis catus) associated with taste perception. The invention provides, inter alia, the nucleotide sequence of the feline Tas1r1, Tas1r2, and Tas1r3 receptor genes, the amino acid sequences of the polypeptides encoded thereby, and antibodies to the polypeptides. The present invention also relates to methods for screening for compounds that modify the genes' function or activity, the compounds identified by such screens, and mimetics of the identified compounds. The invention further provides methods for modifying the taste preferences, ingestive responses, or general behavior of a mammal, such as a cat, by administering compounds that affect the function or activity of the gene or the polypeptide encoded thereby.
Public/Granted literature
- US20090205061A1 Taste Receptors Of The T1R Family From Domestic Cat Public/Granted day:2009-08-13
Information query