Invention Grant
US08173813B2 Quinolone and tetrahydroquinolone and related compounds having NOS inhibitory activity
有权
喹诺酮和四氢喹诺酮及具有NOS抑制活性的相关化合物
- Patent Title: Quinolone and tetrahydroquinolone and related compounds having NOS inhibitory activity
- Patent Title (中): 喹诺酮和四氢喹诺酮及具有NOS抑制活性的相关化合物
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Application No.: US12054083Application Date: 2008-03-24
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Publication No.: US08173813B2Publication Date: 2012-05-08
- Inventor: Shawn Maddaford , Jailall Ramnauth , Suman Rakhit , Joanne Patman , Subhash C. Annedi , John Andrews , Peter Dove , Sarah Silverman , Paul Renton
- Applicant: Shawn Maddaford , Jailall Ramnauth , Suman Rakhit , Joanne Patman , Subhash C. Annedi , John Andrews , Peter Dove , Sarah Silverman , Paul Renton
- Applicant Address: CA Mississauga
- Assignee: NeurAxon, Inc.
- Current Assignee: NeurAxon, Inc.
- Current Assignee Address: CA Mississauga
- Agency: Clark & Elbing LLP
- Main IPC: C07D215/00
- IPC: C07D215/00 ; C07D487/00
Abstract:
The present invention features quinolones, tetrahydroquinolines, and related compounds that inhibit nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions.
Public/Granted literature
- US20080234237A1 QUINOLONE AND TETRAHYDROQUINOLONE AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY Public/Granted day:2008-09-25
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