Invention Grant
US08173861B2 Transgenic pig model for a hereditary neurodegenerative autosomal dominant disease
失效
用于遗传性神经退行性常染色体显性疾病的转基因猪模型
- Patent Title: Transgenic pig model for a hereditary neurodegenerative autosomal dominant disease
- Patent Title (中): 用于遗传性神经退行性常染色体显性疾病的转基因猪模型
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Application No.: US12298974Application Date: 2007-04-30
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Publication No.: US08173861B2Publication Date: 2012-05-08
- Inventor: Lone Bruhn Madsen , Christian Bendixen , Knud Larsen , Connie Jakobsen Juhl , Bo Thomsen
- Applicant: Lone Bruhn Madsen , Christian Bendixen , Knud Larsen , Connie Jakobsen Juhl , Bo Thomsen
- Applicant Address: DK Aarhus C
- Assignee: Aarhus Universitet
- Current Assignee: Aarhus Universitet
- Current Assignee Address: DK Aarhus C
- Agency: Weingarten, Schurgin, Gagnebin & Lebovici LLP
- International Application: PCT/DK2007/000204 WO 20070430
- International Announcement: WO2007/124751 WO 20071108
- Main IPC: C12N15/00
- IPC: C12N15/00 ; A01K67/027 ; G01N33/00
Abstract:
The present invention discloses a non-human animal model for a hereditary autosomal dominant disease. The non-human animal model expresses at least one phenotype associated with the disease and is obtained by a genetic determinant. The invention also relates to sperm cells and embryos comprising the genetic determinant for an autosomal dominant disease. Furthermore, methods for producing the non-human animal model, sperm cell, and embryos are disclosed.
Public/Granted literature
- US20090304595A1 ANIMAL MODEL AND A METHOD FOR PRODUCING AN ANIMAL MODEL Public/Granted day:2009-12-10
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