Invention Grant
- Patent Title: Analysis of molecular interactions on and/or in thin layers
- Patent Title (中): 分析薄层上和/或薄层的分子相互作用
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Application No.: US12672535Application Date: 2008-08-09
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Publication No.: US08174708B2Publication Date: 2012-05-08
- Inventor: Guenter Gauglitz , Guenther Proll , Florian Proell , Lutz Steinle , Markus Schubert
- Applicant: Guenter Gauglitz , Guenther Proll , Florian Proell , Lutz Steinle , Markus Schubert
- Applicant Address: DE Tuebingen
- Assignee: Biametrics Maken und Rechte GmbH
- Current Assignee: Biametrics Maken und Rechte GmbH
- Current Assignee Address: DE Tuebingen
- Agent Jonathan Myers; Andrew Wilford
- Priority: DE102007038797 20070809
- International Application: PCT/EP2008/006587 WO 20080809
- International Announcement: WO2009/019043 WO 20090212
- Main IPC: G01B11/02
- IPC: G01B11/02

Abstract:
The invention relates to a carrier for a thin layer and a method for the analysis of molecular interactions on and/or in such a thin layer. A thin layer disposed on a carrier is illuminated with electromagnetic radiation from at least one radiation source and a reflected radiation part on boundary surfaces of the thin layer is detected by means of an optoelectronic converter that converts the detected radiation into a frequency- and intensity-dependant photocurrent. A reading voltage is applied to the optoelectronic converter. By changing the reading voltage, the spectral sensitivity of the optoelectronic converter is varied such that a substantially constant photocurrent is obtained. Alternatively or in addition to varying the spectral sensitivity by changing the reading voltage, the reflected radiation part is detected with an optoelectronic converter that is designed as a sensor layer in the carrier. The carrier is particularly characterized in that it comprises a substrate on which at least one sensor layer with optoelectronic properties is disposed.
Public/Granted literature
- US20110026034A1 ANALYSIS OF MOLECULAR INTERACTIONS ON AND/OR IN THIN LAYERS Public/Granted day:2011-02-03
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