Provided herein are systems and methods for transmitting signals across a pair of wires. In accordance with specific embodiments, a differential signal is transmitted across the pair of wires during one period of time, and two single-ended signals are transmitted across the same pair of wires during another period of time. Low voltage differential signaling (LVDS) can be used to transmit the differential signal across the pair of wires. In contrast, non-differential signaling can be used to transfer the two singled-ended signals across the same pair of wires.