A technique is used to realize a generalized decision feedback equalizer (GDFE) Precoder for multi-user multiple-input multiple-output (MU-MIMO) systems, which significantly reduces the computational cost while resulting in no capacity loss. The technique is suitable for improving the performance of various MU-MIMO wireless systems including future 4G cellular networks. In one embodiment, a method for configuring a GDFE precoder in a base station of a MU-MIMO wireless system having k user terminals, each user terminal having associated therewith a feedforward filter. The method comprises computing a filter matrix C using one of a plurality of alternative formulas of the invention; and, based on the computation of the filter matrix C, computing a transmit filter matrix B for a transmit filter used to process a symbol vector obtained after a decision feedback equalizing stage of the GDFE precoder, a feedforward filter matrix F, and an interference pre-cancellation matrix G.