A computer-implemented method for detecting a malicious process using file-name heuristics may comprise: 1) identifying a process, 2) identifying a process name for the process, 3) identifying a list of process names for non-malicious processes, and 4) determining, by comparing the process name for the process with the list of process names for non-malicious processes, whether to allow the process to execute. A method for maintaining a database containing information about non-malicious processes is also disclosed. Corresponding systems and computer-readable media are also disclosed.