Invention Grant
- Patent Title: Deracemisation of amines
- Patent Title (中): 胺的脱甲酰化
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Application No.: US12947164Application Date: 2010-11-16
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Publication No.: US08178324B2Publication Date: 2012-05-15
- Inventor: Marina Victorovna Alexeeva , Alexis Enright , Mahmoud Mahmoudian , Nicholas Turner
- Applicant: Marina Victorovna Alexeeva , Alexis Enright , Mahmoud Mahmoudian , Nicholas Turner
- Applicant Address: GB Midlothian
- Assignee: Ingenza Limited
- Current Assignee: Ingenza Limited
- Current Assignee Address: GB Midlothian
- Agency: McDermott Will & Emery LLP
- Agent Avani C. Macaluso
- Priority: GB0206415.2 20020319
- Main IPC: C12P21/06
- IPC: C12P21/06 ; C12P13/00 ; C12N9/06
Abstract:
The present invention relates to a method for the deracemization or chiral inversion of chiral amines by enzymatic treatment. The method employs a stereoselective enzymatic conversion and either a non-selective or partially selective chemical or enzymatic conversion, simultaneously or sequentially. The invention also provides a method for selecting a suitable enzyme, particularly a suitable amine oxidase, and for the generation of novel enzymes suitable for use in the deracemization method.
Public/Granted literature
- US20110065154A1 Deracemisation of Amines Public/Granted day:2011-03-17
Information query
