Invention Grant
- Patent Title: GPCR expression vector
- Patent Title (中): GPCR表达载体
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Application No.: US12820987Application Date: 2010-06-22
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Publication No.: US08178346B2Publication Date: 2012-05-15
- Inventor: Helena S. Mancebo , Jeng-Horng Her , Samuel X. Li , Jianfu L. Wang
- Applicant: Helena S. Mancebo , Jeng-Horng Her , Samuel X. Li , Jianfu L. Wang
- Applicant Address: US CA Hayward
- Assignee: Multispan, Inc.
- Current Assignee: Multispan, Inc.
- Current Assignee Address: US CA Hayward
- Agency: Dorsey & Whitney LLP
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N1/20 ; C12N5/00 ; C12N5/02 ; C12N15/74 ; C12P21/06 ; C07K1/00 ; C07K14/00 ; C07K17/00
Abstract:
The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.
Public/Granted literature
- US20100330591A1 GPCR Expressing Cell Lines and Antibodies Public/Granted day:2010-12-30
Information query
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