Invention Grant
- Patent Title: Histamine H3 receptor agents, preparation and therapeutic uses
- Patent Title (中): 组胺H3受体剂，制剂及治疗用途
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Application No.: US11909727Application Date: 2006-03-28
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Publication No.: US08178528B2Publication Date: 2012-05-15
- Inventor: Philip Arthur Hipskind , Takako Takakuwa , Cynthia Darshini Jesudason , Robert Alan Gadski , William Joseph Hornback , Richard Todd Pickard , Lisa Selsam Beavers
- Applicant: Philip Arthur Hipskind , Takako Takakuwa , Cynthia Darshini Jesudason , Robert Alan Gadski , William Joseph Hornback , Richard Todd Pickard , Lisa Selsam Beavers
- Applicant Address: US IN Indianapolis
- Assignee: Eli Lilly and Company
- Current Assignee: Eli Lilly and Company
- Current Assignee Address: US IN Indianapolis
- Agent Dan L. Wood
- International Application: PCT/US2006/011320 WO 20060328
- International Announcement: WO2006/107661 WO 20061012
- Main IPC: A61K31/535
- IPC: A61K31/535 ; A61K31/497 ; A61K31/445 ; C07D413/00 ; C07D409/00 ; C07D207/00
Abstract:
The present invention discloses novel compounds of Formula (I) or pharmaceutically acceptable salts thereof which have histamine—H3 receptor antagonist or inverse agonist activity, as well as methods and intermediates for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using these compositions to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases.
Public/Granted literature
- US20100160406A1 HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES Public/Granted day:2010-06-24
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