Invention Grant
US08178551B2 Orally bioavailable prodrugs of (+)-3-hydroxymorphinan for Parkinson'S disease prevention or treatment
失效
(+) - 3-羟基吗啡喃的口服生物可利用前药用于帕金森病的预防或治疗
- Patent Title: Orally bioavailable prodrugs of (+)-3-hydroxymorphinan for Parkinson'S disease prevention or treatment
- Patent Title (中): (+) - 3-羟基吗啡喃的口服生物可利用前药用于帕金森病的预防或治疗
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Application No.: US12530444Application Date: 2008-03-07
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Publication No.: US08178551B2Publication Date: 2012-05-15
- Inventor: Jinhwa Lee , Jeongmin Kim , Myung Eun Jung , Jong Yup Kim , Kwang-Seop Song , Eun Jung Son , Suk Ho Lee , Ho Kyun Han , Min Ju Kim , MinWoo Lee
- Applicant: Jinhwa Lee , Jeongmin Kim , Myung Eun Jung , Jong Yup Kim , Kwang-Seop Song , Eun Jung Son , Suk Ho Lee , Ho Kyun Han , Min Ju Kim , MinWoo Lee
- Applicant Address: KR Gyeonggi-Do
- Assignee: Green Cross Corporation
- Current Assignee: Green Cross Corporation
- Current Assignee Address: KR Gyeonggi-Do
- Agency: Sughrue Mion, PLLC
- International Application: PCT/KR2008/001306 WO 20080307
- International Announcement: WO2008/111767 WO 20080918
- Main IPC: A61K31/439
- IPC: A61K31/439 ; C07D221/28

Abstract:
The present invention is directed to a novel prodrug of (+)-3-hydroxymorphinan compound of formula (I) or a pharmaceutically acceptable salt thereof, a method for preparing the same, and its use for preventing or treating Parkinson's disease.
Public/Granted literature
- US20100113500A1 ORALLY BIOAVAILABLE PRODUCTS OF (+)-3-HYDROXYMORPHINAN FOR PARKINSON'S DISEASE PREVENTION OR TREATMENT Public/Granted day:2010-05-06
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