Invention Grant
- Patent Title: Apoptosis signal-regulating kinase 1 inhibitors
- Patent Title (中): 细胞凋亡信号调节激酶1抑制剂
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Application No.: US12490074Application Date: 2009-06-23
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Publication No.: US08178555B2Publication Date: 2012-05-15
- Inventor: Edcon Chang , Stephen L. Gwaltney , Angie Vassar
- Applicant: Edcon Chang , Stephen L. Gwaltney , Angie Vassar
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agent Matthew J. Russo; C. Amy Smith
- Main IPC: A61K31/4365
- IPC: A61K31/4365 ; A61K31/519 ; C07D513/04 ; C07D239/70

Abstract:
The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”) inhibiting compounds of the formula wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
Public/Granted literature
- US20090318425A1 APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS Public/Granted day:2009-12-24
Information query
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