A system and method of predicting telemetry signal dropout creates a prediction of patient destination. The method includes defining a telemetry coverage area, receiving a location of a monitored patient, recording the received location, calculating a trajectory and speed, and comparing the location, trajectory, and speed of the patient to historical patient movement trends to predict patient destination. The system includes a remote unit worn by a patient and at least one telemetry receiver, a location services computer, a patient location database, a location prediction computer, and a graphical display. The location services computer receives the location information and computes a location, speed, and trajectory of the patient. The location prediction computer compares the computed location, speed, and trajectory of the patient to previously acquired locations, speeds, and trajectories to predict a patient destination.