A radioisotope powered thermoelectric vehicle lacking an internal combustion engine. The vehicle may include a commercially available, federally-approved encased radioisotope, sensors, an encased metal heat conductor, a heating element embedded within a heat sink, a plurality of thermoelectric chips mounted around the outer surface of the heat sink, a hollow body surrounding the heat sink with a space present between the heat sink and the hollow body, a power converter, an electric power regulation and distribution system, a magnetic reed relay unit, operational and directional controls, radioisotope thermoelectric power generator, and at least one DC motor mounted to a wheel of the vehicle. A portable lead-lined metal, climate-controlled, and airtight lockbox may house the entire power generating unit providing for more than redundant systems protection. The vehicle is capable of running indefinitely under all weather conditions, without “refueling” for decades and without introducing toxic emissions into the environment.