Invention Grant
US08192961B2 System and methods for nucleic acid sequencing of single molecules by polymerase synthesis
有权
通过聚合酶合成进行单分子核酸测序的系统和方法
- Patent Title: System and methods for nucleic acid sequencing of single molecules by polymerase synthesis
- Patent Title (中): 通过聚合酶合成进行单分子核酸测序的系统和方法
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Application No.: US11923599Application Date: 2007-10-24
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Publication No.: US08192961B2Publication Date: 2012-06-05
- Inventor: John G. K. Williams
- Applicant: John G. K. Williams
- Applicant Address: US CA Menlo Park
- Assignee: Pacific Biosciences of California, Inc.
- Current Assignee: Pacific Biosciences of California, Inc.
- Current Assignee Address: US CA Menlo Park
- Agent Robert H. Reamey; Matthew B. Murphy
- Main IPC: C12P19/34
- IPC: C12P19/34 ; C12Q1/68 ; C12M1/34 ; C07H21/02 ; C07H21/04
Abstract:
This invention relates to improved methods for sequencing and genotyping nucleic acid in a single molecule configuration. The method involves single molecule detection of fluorescent labeled PPi moieties released from NTPs as a polymerase extension product is created.
Public/Granted literature
- US20090082212A1 SYSTEM AND METHODS FOR NUCLEIC ACID SEQUENCING OF SINGLE MOLECULES BY POLYMERASE SYNTHESIS Public/Granted day:2009-03-26
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