Invention Grant
US08193178B2 Thieno- and furo-pyrimidine modulators of the histamine H4 receptor
有权
组胺H 4受体的噻吩并呋喃嘧啶调节剂
- Patent Title: Thieno- and furo-pyrimidine modulators of the histamine H4 receptor
- Patent Title (中): 组胺H 4受体的噻吩并呋喃嘧啶调节剂
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Application No.: US12283700Application Date: 2008-09-12
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Publication No.: US08193178B2Publication Date: 2012-06-05
- Inventor: James P. Edwards , Danielle K. Neff , Deborah M. Smith , Jennifer D. Venable
- Applicant: James P. Edwards , Danielle K. Neff , Deborah M. Smith , Jennifer D. Venable
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Main IPC: C07D243/08
- IPC: C07D243/08 ; C07D491/147 ; A61K31/5513 ; A61K31/5025 ; A61K31/501 ; A61K31/519 ; A61P29/00
Abstract:
Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
Public/Granted literature
- US20090075970A1 Thieno-and furo-pyrimidine modulators of the histamine H4 receptor Public/Granted day:2009-03-19
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