Invention Grant
- Patent Title: Heterocyclic FXR binding compounds
- Patent Title (中): 杂环FXR结合化合物
-
Application No.: US12377307Application Date: 2007-08-29
-
Publication No.: US08193192B2Publication Date: 2012-06-05
- Inventor: Claus Kremoser , Ulrich Deuschle , Ulrich Abel , Andreas Schulz
- Applicant: Claus Kremoser , Ulrich Deuschle , Ulrich Abel , Andreas Schulz
- Applicant Address: DE Ludwigshafen
- Assignee: Phenex Pharmaceuticals AG
- Current Assignee: Phenex Pharmaceuticals AG
- Current Assignee Address: DE Ludwigshafen
- Agency: Kilyk & Bowersox, P.L.L.C.
- Priority: EP06018024 20060829
- International Application: PCT/EP2007/007556 WO 20070829
- International Announcement: WO2008/025539 WO 20080306
- Main IPC: A61K31/50
- IPC: A61K31/50 ; A61K31/501 ; A61K31/497 ; C07D413/00 ; C07D401/00 ; C07D403/00 ; C07D405/00 ; C07D409/00
Abstract:
The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists or partial agonists of the NR1H4 receptor (FXR). The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds, and to a process for the synthesis of said compounds.
Public/Granted literature
- US20100210660A1 Heterocyclic FXR Binding Compounds Public/Granted day:2010-08-19
Information query
