Invention Grant
US08193204B2 Solid forms of (S)-ethyl 2-amino-3-(4-(2-amino-6-((R)-1- (4-chloro-2-(3-methyl-1H-pyrazol-1-YL)phenyl)2,2,2-trifluoroethoxy)-pyrimidin-4-YL)phenyl)propanoate and methods of their use
有权
固体形式的（S）-2-氨基-3-（4-（2-氨基-6 - （（R）-1-（4-氯-2-（3-甲基-1H-吡唑-1-基） ）苯基）2,2,2-三氟乙氧基） - 嘧啶-4-基）苯基）丙酸乙酯及其使用方法
- Patent Title: Solid forms of (S)-ethyl 2-amino-3-(4-(2-amino-6-((R)-1- (4-chloro-2-(3-methyl-1H-pyrazol-1-YL)phenyl)2,2,2-trifluoroethoxy)-pyrimidin-4-YL)phenyl)propanoate and methods of their use
- Patent Title (中): 固体形式的（S）-2-氨基-3-（4-（2-氨基-6 - （（R）-1-（4-氯-2-（3-甲基-1H-吡唑-1-基） ）苯基）2,2,2-三氟乙氧基） - 嘧啶-4-基）苯基）丙酸乙酯及其使用方法
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Application No.: US12237455Application Date: 2008-09-25
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Publication No.: US08193204B2Publication Date: 2012-06-05
- Inventor: Mark S. Bednarz , Susan De Paul , Ramanaiah C. Kanamarlapudi , Anett Perlberg , Haiming Zhang
- Applicant: Mark S. Bednarz , Susan De Paul , Ramanaiah C. Kanamarlapudi , Anett Perlberg , Haiming Zhang
- Applicant Address: US TX The Woodlands
- Assignee: Lexicon Pharmaceuticals, Inc.
- Current Assignee: Lexicon Pharmaceuticals, Inc.
- Current Assignee Address: US TX The Woodlands
- Agent Max Bachrach
- Main IPC: A61K31/505
- IPC: A61K31/505 ; C07D239/02
Abstract:
Solid forms of (S)-ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate and salts thereof are disclosed.
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