Invention Grant
US08193205B2 Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase
有权
取代的吲哚基烷基氨基衍生物作为组蛋白脱乙酰酶的新型抑制剂
- Patent Title: Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase
- Patent Title (中): 取代的吲哚基烷基氨基衍生物作为组蛋白脱乙酰酶的新型抑制剂
-
Application No.: US11572563Application Date: 2005-07-25
-
Publication No.: US08193205B2Publication Date: 2012-06-05
- Inventor: Marc Gustaaf Celine Verdonck , Patrick René Angibaud , Bruno Roux , Isabelle Noëlle Constance Pilatte , Peter Ten Holte , Janine Arts , Kristof Van Emelen
- Applicant: Marc Gustaaf Celine Verdonck , Patrick René Angibaud , Bruno Roux , Isabelle Noëlle Constance Pilatte , Peter Ten Holte , Janine Arts , Kristof Van Emelen
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica N.V.
- Current Assignee: Janssen Pharmaceutica N.V.
- Current Assignee Address: BE Beerse
- Agent Rajiv S. Shah
- Priority: EP04077172 20040728
- International Application: PCT/EP2005/053612 WO 20050725
- International Announcement: WO2006/010750 WO 20060202
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D409/14 ; A61K31/506
Abstract:
This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Public/Granted literature
- US20090124646A1 SUBSTITUTED INDOLYL ALKYL AMINO DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE Public/Granted day:2009-05-14
Information query
