Invention Grant
US08193229B2 Method of treatment using N3 alkylated benzimidazole derivatives as MEK inhibitors
有权
使用N 3烷基化苯并咪唑衍生物作为MEK抑制剂的处理方法
- Patent Title: Method of treatment using N3 alkylated benzimidazole derivatives as MEK inhibitors
- Patent Title (中): 使用N 3烷基化苯并咪唑衍生物作为MEK抑制剂的处理方法
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Application No.: US12824521Application Date: 2010-06-28
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Publication No.: US08193229B2Publication Date: 2012-06-05
- Inventor: Eli M. Wallace , Joseph P. Lyssikatos , Allison L. Marlow , T. Brian Hurley
- Applicant: Eli M. Wallace , Joseph P. Lyssikatos , Allison L. Marlow , T. Brian Hurley
- Applicant Address: US CO Boulder
- Assignee: Array Biopharma Inc.
- Current Assignee: Array Biopharma Inc.
- Current Assignee Address: US CO Boulder
- Agency: Viksnins Harris & Padys PLLP
- Agent John R. Moore, Esq.; Sarah S. Mastous
- Main IPC: A61K31/4184
- IPC: A61K31/4184
Abstract:
Disclosed are methods of treating a hyperproliferative disorder or a disease related to vasculogenesis or angiogenesis in a mammal, comprising administering to said mammal an effective amount of a compound of the formula or a pharmaceutically accepted salt thereof, wherein A, R1, R2, R7, R8, and R9 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals.
Public/Granted literature
- US20100267793A1 METHOD OF TREATMENT USING N3 ALKYLATED BENZIMIDAZOLE DERIVATIVES AS MEK INHIBITORS Public/Granted day:2010-10-21
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