Invention Grant
- Patent Title: Methods for generating monovalent IgG
- Patent Title (中): 产生单价IgG的方法
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Application No.: US11585505Application Date: 2006-10-23
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Publication No.: US08193322B2Publication Date: 2012-06-05
- Inventor: Wei Yan , Michael Wittekind , Carla Forte
- Applicant: Wei Yan , Michael Wittekind , Carla Forte
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Rosemary Sweeney
- Main IPC: C07K16/46
- IPC: C07K16/46 ; C12P21/08

Abstract:
The present invention relates to monovalent antibody, methods of making thereof and therapeutic uses thereof. In particular, the present invention provides a heterodimeric polypeptide comprising an immunoglobulin heavy chain and a fusion protein comprising an immunoglobulin light chain and an Fc molecule.
Public/Granted literature
- US20070105199A1 Methods for generating monovalent IgG Public/Granted day:2007-05-10
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