Invention Grant
- Patent Title: Cancer cell-specific apoptosis-inducing agents that target chromosome stabilization-associated genes
- Patent Title (中): 针对染色体稳定相关基因的癌细胞特异性凋亡诱导剂
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Application No.: US11547770Application Date: 2005-04-08
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Publication No.: US08193332B2Publication Date: 2012-06-05
- Inventor: Motoki Takagi , Kazunobu Futami , Akira Shimamoto , Yasuhiro Furuichi
- Applicant: Motoki Takagi , Kazunobu Futami , Akira Shimamoto , Yasuhiro Furuichi
- Applicant Address: JP Kanagawa
- Assignee: Genecare Research Institute Co., Ltd.
- Current Assignee: Genecare Research Institute Co., Ltd.
- Current Assignee Address: JP Kanagawa
- Agency: Seed IP Law Group PLLC
- Priority: JP2004-115404 20040409
- International Application: PCT/JP2005/006914 WO 20050408
- International Announcement: WO2005/097189 WO 20051020
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C12N315/11
Abstract:
The present inventors discovered that inhibition of the expression of various genes associated with chromosome stabilization induces cancer cell-specific apoptosis and inhibits cell proliferation. Compounds that inhibit expression of a gene associated with chromosome stabilization or inhibit the function of a protein encoded by such a gene are thought to have cancer cell-specific apoptosis-inducing effects.
Public/Granted literature
- US20090028861A1 Cancer cell-specific apoptosis-inducing agents that target chromosome stabilization-associated genes Public/Granted day:2009-01-29
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