Invention Grant
- Patent Title: Gyrase inhibitors and uses thereof
- Patent Title (中): 促旋酶抑制剂及其用途
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Application No.: US12552430Application Date: 2009-09-02
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Publication No.: US08193352B2Publication Date: 2012-06-05
- Inventor: Paul Charifson , David Deininger , Anne-Laure Grillot , Yusheng Liao , Steven Ronkin , Dean Stamos , Emanuele Perola , Tiansheng Wang , Arnaud LeTiran , Joseph Drumm
- Applicant: Paul Charifson , David Deininger , Anne-Laure Grillot , Yusheng Liao , Steven Ronkin , Dean Stamos , Emanuele Perola , Tiansheng Wang , Arnaud LeTiran , Joseph Drumm
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Michael C. Badia
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D403/14 ; A61K31/506 ; A61K31/4439
Abstract:
The present invention relates to compounds that inhibit bacterial gyrase and/or Topo IV and pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infection. Accordingly, the present invention also relates to methods for treating bacterial infections in mammals.
Public/Granted literature
- US20100063069A1 GYRASE INHIBITORS AND USES THEREOF Public/Granted day:2010-03-11
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