Invention Grant
US08193358B2 Process for producing high-purity prasugrel and acid addition salt thereof
有权
制备高纯度普拉格雷及其酸加成盐的方法
- Patent Title: Process for producing high-purity prasugrel and acid addition salt thereof
- Patent Title (中): 制备高纯度普拉格雷及其酸加成盐的方法
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Application No.: US12225762Application Date: 2007-04-06
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Publication No.: US08193358B2Publication Date: 2012-06-05
- Inventor: Masahiko Hagihara , Hiroyuki Miyata , Yukinori Wada , Naoyuki Yokota
- Applicant: Masahiko Hagihara , Hiroyuki Miyata , Yukinori Wada , Naoyuki Yokota
- Applicant Address: JP Tokyo JP Yamaguchi
- Assignee: Daiichi Sankyo Company, Limited,Ube Industries, Ltd.
- Current Assignee: Daiichi Sankyo Company, Limited,Ube Industries, Ltd.
- Current Assignee Address: JP Tokyo JP Yamaguchi
- Agency: Holtz, Holtz, Goodman & Chick, P.C.
- Priority: JP2006-105555 20060406; JP2007-053094 20070302
- International Application: PCT/JP2007/057785 WO 20070406
- International Announcement: WO2007/114526 WO 20071011
- Main IPC: C07D495/04
- IPC: C07D495/04
Abstract:
The present invention is directed to providing prasugrel hydrochloride or the like with a reduced content of OXTP. A method for producing prasugrel hydrochloride with a reduced content of OXTP, comprising dissolving free prasugrel containing OXTP in an inert solvent and adding hydrochloric acid optionally dropwise to the solution for reaction is also provided.
Public/Granted literature
- US20090203729A1 Process for Producing High-Purity Prasugrel and Acid Addition Salt Thereof Public/Granted day:2009-08-13
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