Invention Grant
US08193360B2 Radiolabelled fluorobenzamide analogues, their synthesis and use in diagnostic imaging
有权
放射性标记的氟代苯甲酰胺类似物，它们的合成和用于诊断成像
- Patent Title: Radiolabelled fluorobenzamide analogues, their synthesis and use in diagnostic imaging
- Patent Title (中): 放射性标记的氟代苯甲酰胺类似物，它们的合成和用于诊断成像
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Application No.: US13082215Application Date: 2011-04-07
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Publication No.: US08193360B2Publication Date: 2012-06-05
- Inventor: Robert H. Mach , Zhude Tu
- Applicant: Robert H. Mach , Zhude Tu
- Applicant Address: US MO St. Louis
- Assignee: Washington University
- Current Assignee: Washington University
- Current Assignee Address: US MO St. Louis
- Agency: Zackson Law LLC
- Agent Saul L. Zackson
- Main IPC: C07D217/10
- IPC: C07D217/10
Abstract:
Fluoroalkoxybenzamide compounds which selectively bind Sigma-2 receptors are disclosed. These compounds, when labelled with 18F, can be used as radiotracers for imaging of tumors by positron emission tomography (PET). In addition, these compounds, when labelled with 123I, can be used as radiotracers for imaging of tumors by single photon emission computed tomography (SPECT). Methods for synthesis of these compounds are also disclosed.
Public/Granted literature
- US20110230662A1 RADIOLABELLED FLUOROBENZAMIDE ANALOGUES, THEIR SYNTHESIS AND USE IN DIAGNOSTIC IMAGING Public/Granted day:2011-09-22
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