Invention Grant
- Patent Title: Phosphothiophene and phosphothiazole HCV polymerase inhibitors
- Patent Title (中): 磷酸噻吩和磷酸噻唑HCV聚合酶抑制剂
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Application No.: US12716278Application Date: 2010-03-03
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Publication No.: US08193372B2Publication Date: 2012-06-05
- Inventor: Cyril Dousson , Claire Pierra , Jean-Francois Griffon , Frederic Leroy , Jean-Laurent Paparin , David Dukhan , Dominique Surleraux
- Applicant: Cyril Dousson , Claire Pierra , Jean-Francois Griffon , Frederic Leroy , Jean-Laurent Paparin , David Dukhan , Dominique Surleraux
- Applicant Address: US MA Cambridge
- Assignee: Idenix Pharmaceuticals, Inc.
- Current Assignee: Idenix Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Jones Day
- Main IPC: C07D333/36
- IPC: C07D333/36 ; C07D277/20 ; C07F9/02 ; A61K31/519 ; A61K31/425 ; A61K31/38
Abstract:
Provided herein are phosphothiophene and phosphothiazole compounds, for example, of any of Formulae I, IA, IIA, IIIA, IVA, VA, VIA, VIIA, IB, IIB, IIIB, IVB, VB, VIB and VIIB disclosed herein, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host infected with HCV.
Public/Granted literature
- US20100233123A1 PHOSPHOTHIOPHENE AND PHOSPHOTHIAZOLE HCV POLYMERASE INHIBITORS Public/Granted day:2010-09-16
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