Invention Grant
- Patent Title: Method for enantioselective synthesis of phosphorus-stereogenic phosphines
- Patent Title (中): 磷立体衍生化膦的对映选择性合成方法
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Application No.: US11996008Application Date: 2006-07-28
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Publication No.: US08193392B2Publication Date: 2012-06-05
- Inventor: Corina Scriban , David S. Glueck
- Applicant: Corina Scriban , David S. Glueck
- Applicant Address: US NH Hanover
- Assignee: Trustees of Dartmouth College
- Current Assignee: Trustees of Dartmouth College
- Current Assignee Address: US NH Hanover
- Agency: Licata & Yurrell P.C.
- International Application: PCT/US2006/029230 WO 20060728
- International Announcement: WO2007/016264 WO 20070208
- Main IPC: C07F9/02
- IPC: C07F9/02
Abstract:
The present invention relates to a process for preparing an enantioenriched phosphorus-stereogenic, tertiary phosphine. Secondary phosphines are contacted with an alkyl halide and base in the presence of a chiral metal catalyst thereby producing the enantioenriched phosphorus-stereogenic, tertiary phosphine for subsequent use in homogeneous catalysis reactions.
Public/Granted literature
- US20080193357A1 Method for Enantioselective Synthesis of Phosphorus-Stereogenic Phosphines Public/Granted day:2008-08-14
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