Invention Grant
US08193415B2 Plant expressing mammalian β1,4-galactosyltransferase and β1,3-glucuronyltransferase
有权
植物表达哺乳动物和1,4-甘露糖基转移酶和1,3-葡萄糖醛酸转移酶
- Patent Title: Plant expressing mammalian β1,4-galactosyltransferase and β1,3-glucuronyltransferase
- Patent Title (中): 植物表达哺乳动物和1,4-甘露糖基转移酶和1,3-葡萄糖醛酸转移酶
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Application No.: US12838162Application Date: 2010-07-16
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Publication No.: US08193415B2Publication Date: 2012-06-05
- Inventor: Hendrikus Antonius Cornelis Bakker , Hendrik Jan Bosch
- Applicant: Hendrikus Antonius Cornelis Bakker , Hendrik Jan Bosch
- Applicant Address: NL Wageningen
- Assignee: Stichting Dienst Landbouwkundig Onderzock
- Current Assignee: Stichting Dienst Landbouwkundig Onderzock
- Current Assignee Address: NL Wageningen
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: EP19990203523 19991026; EP19990203524 19991026
- Main IPC: A01H5/00
- IPC: A01H5/00 ; C12N5/04 ; C12N15/82
Abstract:
The invention relates to the field of glycoprotein processing in transgenic plants used as cost efficient and contamination safe factories for the production of recombinant biopharmaceutical proteins or pharmaceutical compositions comprising these. The invention provides a plant comprising a functional mammalian enzyme providing N-glycan biosynthesis that is normally not present in plants, said plant additionally comprising at least a second mammalian protein or functional fragment thereof that is normally not present in plants.
Public/Granted literature
- US20110030108A1 MAMMALIAN-TYPE GLYCOSYLATION IN PLANTS Public/Granted day:2011-02-03
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