The multiple-antenna space multiplexing system using enhancement signal detection comprising: a code modulation module for coding and modulating bit information; a signal transmission module for transmitting the modulated signals; a signal reception module for receiving the signals; a signal form transform module for transforming form of a channel matrix H and the received signal vector r; a signal detection module for detecting the received signals; a signal reconstruction module for reconstructing the detection results of in the signal detection module, and obtaining a detected signal; a demodulation decoding module for demodulating and decoding the output of the signal reconstruction module, and outputting bit information. Compared with the conventional detection methods, the system performance is improved in considering the realization complexity.