Means and methods for optimizing the utilization of monorail-based vehicles carrying a work-in-progress in a clean manufacturing environment. The method includes increasing the number of pick up and drop off points on a primary or secondary monorail transportation network, to amplify the number and frequency of pick up and drop off events per vehicle per circumnavigation of the network or loop. By increasing the number of pick up and drop off events, the empty run or idle time of the corresponding vehicle will decrease, improving utilization and throughput.