The invention provides a device adapted to assist the sterilization of a limb surface, comprising a flexible tubular sleeve, closed at one end, shaped and sized so as to loosely fit, in use, around the limb of a patient whose limb surface is to be sterilized. The sleeve bas limb-sealing means, located close to or at each end of the sleeve, and each capable of forming, in use, a seal between the sleeve and the limb of a patient. The device is particularly suitable to assist in de-contamination of limbs prior to surgery thereon.