Invention Grant
US08206621B2 Use of ethanol as plasticizer for preparing subcutaneous implants containing thermolabile active principles dispersed in a PLGA matrix
失效
使用乙醇作为增塑剂制备含有分散在PLGA基质中的不溶性活性成分的皮下植入物
- Patent Title: Use of ethanol as plasticizer for preparing subcutaneous implants containing thermolabile active principles dispersed in a PLGA matrix
- Patent Title (中): 使用乙醇作为增塑剂制备含有分散在PLGA基质中的不溶性活性成分的皮下植入物
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Application No.: US10562707Application Date: 2004-06-24
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Publication No.: US08206621B2Publication Date: 2012-06-26
- Inventor: Patrice Mauriac , Pierre Marion
- Applicant: Patrice Mauriac , Pierre Marion
- Applicant Address: IE Dublin
- Assignee: Mediolanum Pharmaceuticals Ltd.
- Current Assignee: Mediolanum Pharmaceuticals Ltd.
- Current Assignee Address: IE Dublin
- Agency: Abelman, Frayne & Schwab
- Priority: ITMI2003A1302 20030626
- International Application: PCT/EP2004/051226 WO 20040624
- International Announcement: WO2005/000277 WO 20050106
- Main IPC: B01J13/02
- IPC: B01J13/02 ; B01J13/18 ; A61K9/127
Abstract:
A plasticized polymer of PLGA employing ethanol as the plasticizing agent prepared at a temperature higher than the Tg and lower than the boiling point of ethanol can be used in subcutaneous implants containing active ingredients therein.
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