Invention Grant
US08206701B2 Semi-allogenic anti-tumour vaccine with HLA haplo-identical antigen-presenting cells
有权
具有HLA单倍体相同抗原呈递细胞的半同种异体抗肿瘤疫苗
- Patent Title: Semi-allogenic anti-tumour vaccine with HLA haplo-identical antigen-presenting cells
- Patent Title (中): 具有HLA单倍体相同抗原呈递细胞的半同种异体抗肿瘤疫苗
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Application No.: US10665111Application Date: 2003-09-16
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Publication No.: US08206701B2Publication Date: 2012-06-26
- Inventor: Dolores Schendel , Rudolf Wank
- Applicant: Dolores Schendel , Rudolf Wank
- Applicant Address: DE Neuherberg
- Assignee: Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
- Current Assignee: Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
- Current Assignee Address: DE Neuherberg
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- Main IPC: A61K48/00
- IPC: A61K48/00
Abstract:
The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases.
Public/Granted literature
- US20050175596A1 Semi-allogenic anti-tumour vaccine with HLA haplo-identical antigen-presenting cells Public/Granted day:2005-08-11
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