Invention Grant
- Patent Title: Remedies for ischemia
- Patent Title (中): 缺血治疗
-
Application No.: US12296584Application Date: 2007-04-12
-
Publication No.: US08207116B2Publication Date: 2012-06-26
- Inventor: Wolfgang M. Franz , Hans Theiss , Marc-Michael Zaruba , Stefan Brunner
- Applicant: Wolfgang M. Franz , Hans Theiss , Marc-Michael Zaruba , Stefan Brunner
- Applicant Address: DE Munich
- Assignee: Ludwig-Maximilians-Universitat Munchen
- Current Assignee: Ludwig-Maximilians-Universitat Munchen
- Current Assignee Address: DE Munich
- Agency: Foley & Lardner LLP
- International Application: PCT/EP2007/003272 WO 20070412
- International Announcement: WO2007/118680 WO 20071025
- Main IPC: A61K38/16
- IPC: A61K38/16 ; A61K38/19 ; A61K38/29

Abstract:
The present invention relates to uses and methods of parathyroid hormone (PTH), preferably PTH (1-34), and/or parathyroid hormone-related peptide (PTHrP), preferably PTHrP (1-34), for recruiting stem cells into tissue suffering from ischemia, wherein said stem cells are preferably capable of repairing and/or regenerating said tissue suffering from ischemia. Accordingly, the uses and methods of the present invention are preferably suitable for the prevention and/or treatment of ischemia. Moreover, the present invention relates to a composition comprising parathyroid hormone (PTH), preferably PTH (1-34), and/or parathyroid hormone-related peptide (PTHrP), preferably PTHrP (1-34), and/or G-CSF or a G-CSF fragment for use as a pharmaceutical composition. In a particular aspect, a DPP IV antagonist is applied in the uses, methods and/or compositions of the present invention.
Public/Granted literature
- US20090286730A1 REMEDIES FOR ISCHEMIA Public/Granted day:2009-11-19
Information query
IPC分类: