Invention Grant
US08207134B2 Fused ring spiroketal derivative and use thereof as anti-diabetic drug
失效
稠环螺旋酮衍生物及其作为抗糖尿病药物的用途
- Patent Title: Fused ring spiroketal derivative and use thereof as anti-diabetic drug
- Patent Title (中): 稠环螺旋酮衍生物及其作为抗糖尿病药物的用途
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Application No.: US12375378Application Date: 2007-07-27
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Publication No.: US08207134B2Publication Date: 2012-06-26
- Inventor: Tsutomu Sato , Yoshihito Ohtake , Masahiro Nishimoto , Takashi Emura , Takamitsu Kobayashi , Marina Yamaguchi , Kyouko Takami
- Applicant: Tsutomu Sato , Yoshihito Ohtake , Masahiro Nishimoto , Takashi Emura , Takamitsu Kobayashi , Marina Yamaguchi , Kyouko Takami
- Applicant Address: JP Tokyo
- Assignee: Chugai Seiyaku Kabushiki Kaisha
- Current Assignee: Chugai Seiyaku Kabushiki Kaisha
- Current Assignee Address: JP Tokyo
- Agency: Browdy and Neimark, PLLC
- Priority: JP2006-205242 20060727
- International Application: PCT/JP2007/064802 WO 20070727
- International Announcement: WO2008/013277 WO 20080131
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70 ; C07H1/00 ; C07H3/00 ; C08B37/00

Abstract:
Provided are a compound represented by Formula (I): wherein R1, R2, R3, and R4 are each independently selected from a hydrogen atom, a C1-6 alkyl group which may be substituted, a C7-14 aralkyl group which may be substituted and —C(═O)Rx; n denotes an integer selected from 1 and 2; and ring Ar is selected from the groups represented by the following Formula (a) to (f). or a prodrug thereof or a pharmaceutically acceptable salt thereof as well as a pharmaceutical agent and a pharmaceutical composition containing such a compound or a prodrug thereof, or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20100234609A1 FUSED RING SPIROKETAL DERIVATIVE AND USE THEREOF AS ANTI-DIABETIC DRUG Public/Granted day:2010-09-16
Information query
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