Invention Grant
US08207153B2 Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
有权
喹唑啉酮作为人磷脂酰肌醇3-激酶三角体的抑制剂
- Patent Title: Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
- Patent Title (中): 喹唑啉酮作为人磷脂酰肌醇3-激酶三角体的抑制剂
-
Application No.: US12732128Application Date: 2010-03-25
-
Publication No.: US08207153B2Publication Date: 2012-06-26
- Inventor: Kerry W. Fowler , Danwen Huang , Edward A. Kesicki , Hua Chee Ooi , Amy Oliver , Fuqiang Ruan , Jennifer Treiberg
- Applicant: Kerry W. Fowler , Danwen Huang , Edward A. Kesicki , Hua Chee Ooi , Amy Oliver , Fuqiang Ruan , Jennifer Treiberg
- Applicant Address: US WA Bothell
- Assignee: ICOS Corporation
- Current Assignee: ICOS Corporation
- Current Assignee Address: US WA Bothell
- Agency: Morrison & Foerster LLP
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A01N43/00 ; C07D473/00 ; C07D239/72
Abstract:
Compounds that inhibit P13Kδ activity, including compounds that selectively inhibit P13Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (P13Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which P13Kδ plays a role in leukocyte function, using the compounds also are disclosed.
Public/Granted literature
- US20100256168A1 QUINAZOLINONES AS INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA Public/Granted day:2010-10-07
Information query
IPC分类:
