Invention Grant
US08207161B2 Tetrahydro-imidazo[1,5-α]pyrazine derivatives, preparation process and medicinal use thereof
有权
四氢 - 咪唑并[1,5-α]吡嗪衍生物，的制备方法和药物用途
![Tetrahydro-imidazo[1,5-α]pyrazine derivatives, preparation process and medicinal use thereof](/docs/US/2012-06-26/US08207161B2/abs.jpg.600x600.jpg)
- Patent Title: Tetrahydro-imidazo[1,5-α]pyrazine derivatives, preparation process and medicinal use thereof
- Patent Title (中): 四氢 - 咪唑并[1,5-α]吡嗪衍生物，的制备方法和药物用途
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Application No.: US12743795Application Date: 2008-11-27
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Publication No.: US08207161B2Publication Date: 2012-06-26
- Inventor: Peng Cho Tang , Fanglong Yang , Jiang Fan , Hu Feng , Yang Wang , Tao Yang
- Applicant: Peng Cho Tang , Fanglong Yang , Jiang Fan , Hu Feng , Yang Wang , Tao Yang
- Applicant Address: CN Jiangsu CN Shanghai
- Assignee: Jiangsu Hengrui Medicine Co. Ltd.,Shanghai Hengrui Pharmaceutical Co. Ltd.
- Current Assignee: Jiangsu Hengrui Medicine Co. Ltd.,Shanghai Hengrui Pharmaceutical Co. Ltd.
- Current Assignee Address: CN Jiangsu CN Shanghai
- Agency: Brinks Hofer Gilson & Lione
- Agent Ryan L. Marshall
- Priority: CN200710302335 20071226
- International Application: PCT/CN2008/001936 WO 20081127
- International Announcement: WO2009/082881 WO 20090709
- Main IPC: A61K31/541
- IPC: A61K31/541 ; A61K31/5377 ; A61K31/519 ; C07D487/04 ; C07D413/14 ; C07D279/12 ; C12N9/99 ; A61P3/10 ; A61P3/04
![Tetrahydro-imidazo[1,5-α]pyrazine derivatives, preparation process and medicinal use thereof](/abs-image/US/2012/06/26/US08207161B2/abs.jpg.150x150.jpg)
Abstract:
Tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I), their preparation methods, pharmaceutical compositions containing the derivatives and uses thereof as medicaments, especially as dipeptidyl peptidase IV inhibitors, wherein the substituents of formula (I) are defined as same as the description.
Public/Granted literature
- US20100273786A1 TETRAHYDRO-IMIDAZ0[1,5-A]PYRAZINE DERIVATIVES, PREPARATION PROCESS AND MEDICINAL USE THEREOF Public/Granted day:2010-10-28
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