Invention Grant
US08207186B2 Benzocycloheptapyridines as inhibitors of the receptor tyrosine kinase MET
有权
苯并环庚啶作为受体酪氨酸激酶MET的抑制剂
- Patent Title: Benzocycloheptapyridines as inhibitors of the receptor tyrosine kinase MET
- Patent Title (中): 苯并环庚啶作为受体酪氨酸激酶MET的抑制剂
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Application No.: US11921350Application Date: 2006-06-22
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Publication No.: US08207186B2Publication Date: 2012-06-26
- Inventor: James P. Jewell , Jason D. Katz
- Applicant: James P. Jewell , Jason D. Katz
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent David A. Muthard
- International Application: PCT/US2006/024247 WO 20060622
- International Announcement: WO2007/002254 WO 20070104
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; C07D221/00
Abstract:
The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine compounds, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
Public/Granted literature
- US20090197908A1 Benzocycloheptapyridines as inhibitors of the receptor tyrosine kinase met Public/Granted day:2009-08-06
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