Invention Grant
US08207193B2 Quiniclidine derivatives of (hetero) arylcycloheptanecarboxylic acid as muscarinic receptor antagonists
失效
（杂）芳基环庚烷羧酸的喹啉衍生物作为毒蕈碱受体拮抗剂
- Patent Title: Quiniclidine derivatives of (hetero) arylcycloheptanecarboxylic acid as muscarinic receptor antagonists
- Patent Title (中): （杂）芳基环庚烷羧酸的喹啉衍生物作为毒蕈碱受体拮抗剂
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Application No.: US12514509Application Date: 2007-11-13
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Publication No.: US08207193B2Publication Date: 2012-06-26
- Inventor: Rhonan Ford , Andrew Mather , Antonio Mete
- Applicant: Rhonan Ford , Andrew Mather , Antonio Mete
- Applicant Address: SE Sodertalje
- Assignee: Astrazeneca AB
- Current Assignee: Astrazeneca AB
- Current Assignee Address: SE Sodertalje
- Agency: Astrazeneca AB
- International Application: PCT/GB2007/004350 WO 20071113
- International Announcement: WO2008/059245 WO 20080522
- Main IPC: A61K31/439
- IPC: A61K31/439 ; C07D453/02 ; A61P11/00
Abstract:
The invention provides compounds of formula (I) wherein R4 is a group of formula (II) or (IIIa) or (IIIb) and R1, R2, R3, R5, a, b and X are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them, a process for preparing pharmaceutical compositions, their use in therapy and intermediates of use in their preparation (I), (II), (IIIa), (IIIb).
Public/Granted literature
- US20100029713A1 QUINICLIDINE DERIVATIVES OF (HETERO) ARYLCYCLOHEPTANECARBOXYLIC ACID AS MUSCARINIC RECEPTOR ANTAGONISTS Public/Granted day:2010-02-04
Information query
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