Invention Grant
- Patent Title: Triazole derivatives as SCD inhibitors
- Patent Title (中): 三唑衍生物作为SCD抑制剂
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Application No.: US12741629Application Date: 2008-11-07
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Publication No.: US08207204B2Publication Date: 2012-06-26
- Inventor: Anne Marie Jeanne Bouillot , Alain Laroze
- Applicant: Anne Marie Jeanne Bouillot , Alain Laroze
- Applicant Address: US PA Philadelphia
- Assignee: GlaxoSmithKline LLC
- Current Assignee: GlaxoSmithKline LLC
- Current Assignee Address: US PA Philadelphia
- Agent Dara L. Dinner; Theodore Furman
- Priority: GB0722075.9 20071109
- International Application: PCT/EP2008/065105 WO 20081107
- International Announcement: WO2009/060054 WO 20090514
- Main IPC: A61K31/4192
- IPC: A61K31/4192 ; A61K31/4245 ; C07D249/06 ; C07D413/10

Abstract:
The present invention relates to substituted triazole compounds of the formula (I): and salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for inhibiting SCD activity, such as diseases related to elevated lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome, skin disorders such as acne, diseases or conditions related to cancer and the treatment of symptoms linked to the production of the amyloid plaque-forming Aβ42 peptide such as Alzheimer's disease and the like.
Public/Granted literature
- US20100297097A1 COMPOUNDS Public/Granted day:2010-11-25
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