Invention Grant
- Patent Title: Crystalline polymorphs of a CXC-chemokine receptor ligand
- Patent Title (中): CXC-趋化因子受体配体的结晶多晶型物
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Application No.: US12174470Application Date: 2008-07-16
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Publication No.: US08207221B2Publication Date: 2012-06-26
- Inventor: Mengwei Hu , Younong Yu , Michael P. Dwyer , Arthur G. Taveras , Agnes Kim-Meade , Jianguo Yin , Xiaoyong Fu , Timothy L. McAllister , Shuyi Zhang , Kevin Klopfer
- Applicant: Mengwei Hu , Younong Yu , Michael P. Dwyer , Arthur G. Taveras , Agnes Kim-Meade , Jianguo Yin , Xiaoyong Fu , Timothy L. McAllister , Shuyi Zhang , Kevin Klopfer
- Applicant Address: US NJ Kenilworth
- Assignee: Schering Corporation
- Current Assignee: Schering Corporation
- Current Assignee Address: US NJ Kenilworth
- Agent Patricia A Shatynski; Valerie J. Camara
- Main IPC: A61K31/341
- IPC: A61K31/341 ; C07D307/504
Abstract:
The present invention relates to four distinct crystalline polymorphs of a monohydrate of Compound A having the following chemical structure: These four polymorphic forms, herein referred to as Forms I, II, III and IV are active as a CXC-chemokine receptor ligands. The invention is further directed to formulations, methods of treatment, and processes of synthesis of these polymorphic forms.
Public/Granted literature
- US20080279822A1 Crystalline Polymorphs of a CXC-Chemokine Receptor Ligand Public/Granted day:2008-11-13
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