Invention Grant
- Patent Title: Antibody antagonists of interleukin-13 receptor α1
- Patent Title (中): 白细胞介素-13受体α1的抗体拮抗剂
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Application No.: US12445759Application Date: 2007-10-19
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Publication No.: US08207304B2Publication Date: 2012-06-26
- Inventor: Andrew Donald Nash , Louis Jerry Fabri , Dennis Zaller , William R. Strohl , Zhiqiang An
- Applicant: Andrew Donald Nash , Louis Jerry Fabri , Dennis Zaller , William R. Strohl , Zhiqiang An
- Applicant Address: AU Parkville
- Assignee: CSL Limited
- Current Assignee: CSL Limited
- Current Assignee Address: AU Parkville
- Agency: Licata & Tyrrell P.C.
- International Application: PCT/US2007/081889 WO 20071019
- International Announcement: WO2008/049098 WO 20080424
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12N15/13

Abstract:
Antibody antagonists of human interleukin-13 receptor alpha 1 are disclosed. The antibody molecules are useful in the inhibition of IL-13Rα1-mediated activities and, accordingly, present desirable antagonists for the use in the treatment of conditions associated with hIL-13Rα activity. The present invention also discloses nucleic acid encoding said antibody molecules, vectors, host cells, and compositions comprising the antibody molecules. Methods of using the antibody molecules for inhibiting or antagonizing IL-13Rα1-mediated activities are also disclosed.
Public/Granted literature
- US20090285799A1 Antibody Antagonists of Interleukin-13 Receptor Alpha1 Public/Granted day:2009-11-19
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