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US08207304B2 Antibody antagonists of interleukin-13 receptor α1 有权
白细胞介素-13受体α1的抗体拮抗剂

Antibody antagonists of interleukin-13 receptor α1
Abstract:
Antibody antagonists of human interleukin-13 receptor alpha 1 are disclosed. The antibody molecules are useful in the inhibition of IL-13Rα1-mediated activities and, accordingly, present desirable antagonists for the use in the treatment of conditions associated with hIL-13Rα activity. The present invention also discloses nucleic acid encoding said antibody molecules, vectors, host cells, and compositions comprising the antibody molecules. Methods of using the antibody molecules for inhibiting or antagonizing IL-13Rα1-mediated activities are also disclosed.
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